The Two Supplements Pharmacists Are Now Recommending Most

A major new report shows just how much the advice at the pharmacy counter is changing. When researchers surveyed hundreds of pharmacists across the country this year, two supplements stood out as ones they are increasingly recommending.

These two very worthy supplements are creatine and collagen. Two of the exact nutrients I have been writing about and championing for women, now stepping into the spotlight as the most  pharmacist recommended supplements in the country. If you have been on the fence about either one, now is the time to listen to the professionals who see health up close every day. 

What the New Report Found

In partnership with a major research firm, a survey of 357 pharmacists across the United States were asked which brands and products they most recommend to the people they serve. For the first time, the report added creatine and collagen peptides, a direct reflection of how often these two are now being suggested.

The report described a real shift in how experts think about supplements, away from generic, one-size-fits-all multivitamins and toward what they called precision supplementation, targeted nutrients chosen for specific goals like strength, healthy aging, and vitality. In other words, pharmacists are moving past “take a little of everything” and toward “take the specific things that are actually shown to help.” At the top of that new, more precise list sit creatine and collagen.

Why Creatine Earned Its Place

For thirty years, creatine was marketed almost entirely to men, wrapped in images of barbells and protein shakes, which is exactly why so many women assumed it was not for them. That assumption may be one of the most costly misunderstandings in women’s health, because the truth is the opposite. Women naturally store roughly 70 to 80 percent less creatine than men, so we begin from a much smaller reserve of the very molecule that fuels our muscles and our minds.

Creatine is not a drug or a stimulant. It is a compound your body already makes and uses to regenerate cellular energy. For women, especially through perimenopause and menopause, that energy support translates into real benefits. Research links it to strength and lean muscle, bone health, mood, and mental clarity, many of the exact areas where midlife hits hardest. It will not make you bulky, because women’s hormones simply do not work that way.  What it can do is help you stay strong, sharp, and capable.

I have written about all of this in depth, so if you want the fuller picture, start with Creatine Isn’t a “Man’s Supplement”, which unpacks that 70-to-80-percent gap and why women may have the most to gain. Then, if the brain-energy side fascinates you, The 200-Year Journey of the Most Misunderstood Brain Energy Molecule traces how science came to understand creatine as fuel for the mind, not just the muscles.

Why Collagen Earned Its Place

Collagen is the most abundant protein in your body, the scaffolding that holds together your skin, your joints, and even the framework inside your bones. Starting around our mid-twenties, our natural collagen production begins to slow, and that gradual loss is behind so much of what we notice as we age, from fine lines and less springy skin to stiffer joints and thinning bone.

Supplementing with collagen peptides, the small, well-absorbed form used in the research, gives your body the building blocks to help replenish what time takes away. The evidence supports benefits for skin firmness and hydration, joint comfort, and hair and nail strength, and newer research points to something I find especially important for women, a role in supporting bone. Because your bones are built on a collagen framework, feeding that framework may help protect the strength we most need to preserve after menopause.

There is one more thing I never want women to miss about collagen, and it is the reason I always mention its perfect partner. Your body cannot build stable collagen without vitamin C, which acts as the required cofactor that locks collagen into its strong structure. Collagen delivers the bricks, and vitamin C is the mortar. I explained the bone connection and this pairing in full in my article on collagen, your bones, and vitamin C, which is well worth a read if collagen is new to your routine.

Better Together: The Midlife Duo

Here is what I love most about seeing these two rise together. Creatine and collagen are complementary, each covering ground the other does not, and between them they support an enormous share of what women care about through midlife.

One supports the strength and energy inside you. The other supports the structure that holds you together. Taken consistently, as a daily habit rather than an occasional afterthought, they are a genuinely smart foundation for aging with vitality. It is no wonder the professionals are recommending both.

How to Make Them Work for You

If this is the nudge that finally gets you started, here is how I would approach each, simply and sustainably.

The Bottom Line
It is a wonderful thing when the science you have believed in for years finally becomes the mainstream advice.  Creatine and collagen were never fringe, never just for athletes or beauty magazines.  They are two of the most studied, most practical tools a woman can use to age with strength, clarity, and confidence, and now the professionals at the pharmacy counter are saying so too. 
If you have been waiting for a sign to begin, let this be it.  Start with the researched forms, be kind to your stomach, pair collagen with its vitamin C partner, stay consistent, and give your body the building blocks it has been asking for.  Your strong, capable future self will thank you.
To your strength and vitality,
Naomi

1.    U.S. News & World Report and The Harris Poll. 2026–2027 Best OTC Medicine & Health Products: pharmacist-recommended vitamins and supplements. Survey of 357 pharmacists and 129 dermatologists, March 2026.

2.    Smith-Ryan AE, Cabre HE, Eckerson JM, Candow DG. Creatine supplementation in women’s health: a lifespan perspective. Nutrients. 2021;13(3):877.

3.    Chilibeck PD, Candow DG, et al. Effects of creatine and resistance training on bone health in postmenopausal women. Med Sci Sports Exerc. 2015;47(8):1587–1595.

4.    König D, et al. Specific collagen peptides improve bone mineral density and bone markers in postmenopausal women: a randomized controlled study. Nutrients. 2018;10(1):97.

5.    Proksch E, et al. Oral supplementation of specific collagen peptides has beneficial effects on human skin physiology. Skin Pharmacol Physiol. 2014;27(1):47–55.

6.    Pullar JM, Carr AC, Vissers MCM. The roles of vitamin C in skin health. Nutrients. 2017;9(8):866.

This article is for educational purposes only and is not a substitute for personalized medical advice. Statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease. Pharmacist recommendations reflect a survey of product categories and brands and are not an endorsement of any individual product. Always consult your healthcare provider before starting a new supplement.